you need to match the size perfectly else the pointer will drift away as you move. is your lcd bigger than the tablet?
Only bigger vertically as the tablet's active area is 7" 4:3 ratio (6 x 5") and the Mimo USB monitor is 7" 16:9 ratio (I think). Might as well confess, I'm using a Hanvon ArtMaster tablet as I didn't want to bother with another Wacom since I failed miserably the last time. Hanvon's drivers allow you to choose which monitor to set the tablet to and apparently allow you to set it to a part of the monitor, but somehow I can't get that bit to work. I've even tried the auto settings, but nothing.
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It's a shame as it has some really good specs and the board itself is actually much smaller than the casing meaning I can make a smaller case for it and make it even more portable. I have emailed Tablet Kiosk (known for their good, but extraordinarily expensive tablet PCs) if they could sell me a Wacom digitiser board from one of their discontinued 7" models. I'm not expecting to hear from them, but it's worth a try. Ever that or I get a cheap small Wacom and try again. I did see someone make a DIY Cintiq from one of the old Bamboos (the one with the touch wheel) and someone even made one from a Lapazz tablet (UC-Logic) and it looks like it worked well.
EDIT: Found a US eBay seller with faulty Entourage Pocket Edge tablets for sale. They're 7" and "penabled". Worth looking into to see if one can be modified to work via USB. I'd substitute high pressure levels and whatever for a perfect jitter-free no fuss build!
EDIT 2: Crap. The Entourage Pocket Edge has a 6" digitiser which is just plain stupid. Why have one screen smaller than the other?! And then still charge a lot for the whole product? It's a real shame as the seller was willing to help. I *could* look for a bigger LCD to work with the Mimo's controller board, but it's not easy finding one that will have the same connector and compatible pinout...